1999-2000 Wednesday Slide Conference 9
Diagnoses

 

Case 1 Contrib# 98-0712 AFIP# 2677999 CD1xC57Bl/6 mouse (Mus musculus)

ABC

Case 9-1. A) Distended abdomen. B) Within the left upper quadrant there is a 2.5x3.5cm cystic brown-pink mass. C) The left kidney is replaced by a (now ruptured) thin walled cystic structure with a multilobular, sessile, white mass extending from the wall.

Morphologic Diagnosis: Renal pelvis: Transitional cell carcinoma, with hydronephrosis and chronic-active inflammation.

Etiology: Unknown.

Disease: Transitional cell carcinoma.

 

Case 2 Contrib# Case1  AFIP# 2505896 CD-1 VAF mouse (Mus musculus)

Case 9-2.

Morphologic Diagnosis: Liver: Histiocytic sarcoma.

Etiology: Unknown

Disease: Histiocytic sarcoma.

 

Case 3 Contrib# NIAH  AFIP# 2681359 Canine

Case 9-3.

Morphologic Diagnosis: Lung: Bronchopneumonia, proliferative and necrotizing, subacute, diffuse, moderate, with large basophilic and eosinophilic intranuclear inclusion bodies and small eosinophilic intracytoplasmic inclusion bodies, consistent with canine adenovirus-2 and canine distemper virus

Lung: Bronchopneumonia, proliferative and necrotizing, subacute, diffuse, moderate, with large basophilic and eosinophilic intranuclear inclusion bodies and small eosinophilic intracytoplasmic inclusion bodies.

Etiology:

1) Canine adenovirus-2 (Genus Mastadenovirus, Family Adenoviridae)

2) Canine distemper virus (Genus Morbillivirus, Family Paramyxoviridae)

Disease:

1) Canine distemper

2) Canine adenoviral pneumonia

 

Case 4 Contrib# 11142-98 AFIP# 2679507 Beaver (Castor canadensis) 

AB

Case 9-4. A) There are diffusely distributed variably sized white to tan (necrotic) foci replacing hepatic parenchyma. B) On cut section, the spleen contains multiple variably sized 2-5mm (necrotic) foci.

Morphologic Diagnosis: Liver and spleen: Hepatitis and splenitis, necrotizing, acute, multifocal, moderate, with multifocal necrotizing vasculitis.

Etiology: Francisella tularensis subsp. palaeartica (Type B)

Disease: Tularemia