3-2. Liver, mouse. (HE | -114X)
Granulomas are centered on numerous schostosome eggs with a refractile brown shell, which contain a multinucleated miracidium. Cross sections of the ends of eggs are brownish yellow (arrow). The surrounding hepatic parenchyma contains numerous hypertrophic Kupffer cells which often contain brownish granular pigment (hemozoin). There is a focus of extramedullary hematopoiesis within the liver parenchyma at right.

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