JPC SYSTEMIC PATHOLOGY

RESPIRATORY SYSTEM

September 2017

P-P19 (NP)

 

Signalment (JPC #1947594):  A male gamebird

HISTORY:  From a backyard flock in which all birds had a history of lameness

HISTOPATHOLOGIC DESCRIPTION:  Lung:  Multifocally expanding the interstitium of approximately 50% of the parabronchi and secondary bronchi, and extending into the adjacent pulmonary parenchyma are nodular to coalescing infiltrates consisting of moderate numbers of macrophages and fewer lymphocytes and plasma cells that are often admixed with intrahistiocytic and extracellular brown, granular, anisotropic material (mite pigment).  Parabronchial lumina frequently contain cross and tangential sections of adult arthropods (mites) that are up to 400 um in diameter and are characterized by a thin yellow anisotropic chitinous exoskeleton, multiple jointed appendages, body cavity, and bands of striated muscle.  Multifocally, fragments of degenerate mites and occasional small colonies of basophilic cocci are surrounded by granulomatous inflammation consisting of epitheloid macrophages, multinucleated giant cells (Langhan’s and foreign body type), fewer lymphocytes, plasma cells, small numbers of viable and degenerate heterophils, and occasional clusters of fibroblasts. Rarely, mesobronchi and secondary bronchi are lined by mildly hyperplastic epithelium and contain a moderate amount of intraluminal, granular to fibrillar, lightly eosinophilic material (fibrin) admixed with mild hemorrhage, low numbers of macrophages, sloughed epithelial cells, and sections of degenerate mites.

MORPHOLOGIC DIAGNOSIS:  Lung:  Pneumonia, granulomatous, multifocal, moderate, with parabronchial intraluminal arthropod parasites and colonies of cocci, gamebird, avian.  

ETIOLOGIC DIAGNOSIS:  Pulmonary acariasis

CAUSE:  Cytodites nudus

CONDITION:  Air sac mite infestation

GENERAL DISCUSSION:

LIFE CYCLE: 

TYPICAL CLINICAL FINDINGS:

TYPICAL GROSS FINDINGS:

TYPICAL LIGHT MICROSCOPIC FINDINGS:

ADDITIONAL DIAGNOSTIC TESTS:

DIFFERENTIAL DIAGNOSIS (Bird Lung Mites):

COMPARATIVE PATHOLOGY:  

Lung Mites:

REFERENCES:

  1. Abdul-Aziz T, Fletcher OJ, Barnes HJ. Avian histopathology.  4th ed.  Madison, WI: American Association of Avian Pathologists; 2016:199, 254-255.
  2. Bowman DD. Georgi’s Parasitology for Veterinarians. 9th ed. Philadelphia, PA: WB Saunders; 2009:60-63.
  3. Gardiner CH, Poynton SL. An Atlas of Metazoan Parasites in Animal Tissues. Washington, DC: Armed Forces Institute of Pathology; 1999:56-58.
  4. Macwhirter P. Passeriformes. In: Ritchie BW, Harrison GJ, Harrison LR, eds. Avian Medicine: Principles and Application. Lake Worth, FL: Wingers Publishing, Inc; 1994:1195.
  5. McMullin PF. Parasitic diseases. In: Pattison M, McMullin PF, Bradbury JM, Alexander D, eds. Poultry Diseases. 6th ed. Philadelphia, PA: Elsevier Ltd; 2008:465-6.
  6. Schmidt RE, Reavill DR, Phalen DN. Pathology of pet and aviary birds.  2nd ed. Ames, IA: Wiley; 2015:33, 39-41.

 


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