JPC SYSTEMIC PATHOLOGY

INTEGUMENTARY SYSTEM

November 2016

I-P09 (NP)

 

Signalment (JPC # 1757055):  Flying squirrel (Glaucomys sabrinus)

HISTORY:  Cutaneous mass located beneath the ear

HISTOPATHOLOGIC DESCRIPTION:  Haired skin:  Diffusely hair follicles are markedly expanded and occasionally disrupted by numerous arthropods that are 80 to 100 um in diameter, have a smooth chitinous exoskeleton, jointed appendages, bands of striated muscle, and a reproductive tract which often contains abundant 4um basophilic bodies. Admixed with arthropods are abundant neutrophils and fewer eosinophils and macrophages, keratin, and cellular debris.  The follicular epithelium is hyperplastic with cells piled up to 15 cells thick, with hyperkeratosis, or occasionally is attenuated.  Multifocally there is intracellular and intercellular edema within the follicular epithelium.  Diffusely expanding the dermis are many lymphocytes, plasma cells, macrophages, and plump fibroblasts.  In areas of ruptured follicles (furunculosis), there are similar infiltrates admixed with neutrophils, eosinophils, hemorrhage, and.  Multifocally within follicles there are mite eggs measuring 40 um x 60 um.

MORPHOLOGIC DIAGNOSIS:  Haired skin:  Folliculitis and furunculosis, eosinophilic and neutrophilic, chronic, diffuse, moderate, with marked follicular ectasia, hyperkeratosis, and intrafollicular arthropods, flying squirrel (Glaucomys sabrinus), rodent.

ETIOLOGIC DIAGNOSIS:  Epidermal acariasis

CAUSE:  Psorergates simplex

GENERAL DISCUSSION:

PATHOGENESIS:

TYPICAL GROSS FINDINGS:

TYPICAL LIGHT MICROSCOPIC FINDINGS:

DIFFERENTIAL DIAGNOSIS:

COMPARATIVE PATHOLOGY:

REFERENCES:

  1. Atkins A, Heard DJ, Mertins JW, Kimbro J, Greiner EC. Hyperplastic dermatitis associated with acariasis in a siamang (Symphalangus syndactylus). J Zoo Wildl Med. 2008:39(4):638-41.
  2. Bowman D. Georgis' Parasitology for Veterinarians. 9th ed. St Louis, MO: W.B. Saunders; 2009:73.
  3. Flynn R. Parasites of Laboratory Animals. Ames, IA: Iowa State University Press; 1973:441-444.
  4. Mauldin EA, Peters-Kennedy J. Integumentary system. In: Maxie MG, ed. Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals. Vol 1. 6th ed. Philadelphia, PA: Elsevier Saunders; 2015:678.
  5. Muller G, Scott D, Miller W, Griffin C. Veterinary Dermatology. 6th ed. Philadelphia, PA: W.B. Saunders; 2001:1443.
  6. Percy D, Barthold S. Pathology of Laboratory Rabbits and Rodents. 4th ed. Ames, IA: Blackwell Publishing Professional; 2016:87.


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