JPC SYSTEMIC PATHOLOGY
DIGESTIVE SYSTEM
October 2018
D-P24 (NP)

Signalment (JPC #1817473):  Young horse

HISTORY:  At necropsy, there were numerous elevated subserosal masses in the terminal small intestine that ranged in color from bright red to yellow and brown.

HISTOPATHOLOGIC DESCRIPTION:  Small intestine:  Multifocally, the serosa is expanded up to 1 mm by numerous small-caliber vessels, minimal hemorrhage, increased fibrous connective tissue, moderate numbers of macrophages, lymphocytes, plasma cells, fewer eosinophils, ectatic lymphatics and increased clear space (edema). Macrophages often contain cellular debris and there is multifocal moderate erythrophagocytosis and hemosiderosis.  Multifocally, the submucosa is expanded up to 3 mm thick by edema.  Diffusely the submucosa and lamina propria are infiltrated by mild numbers of previously described inflammatory cells.  Few intestinal crypts contain necrotic debris and neutrophils (crypt abscesses) and there is mild blunting of intestinal villi.

MORPHOLOGIC DIAGNOSIS: 

  1. 1. Small intestine, serosa:  Serositis, lymphoplasmacytic and histiocytic, subacute, multifocal, moderate, with fibrosis, erythrophagocytosis, hemosiderosis and edema, horse, breed unspecified, equine.
  2. Small intestine: Enteritis, lymphoplasmacytic, chronic, diffuse, mild, with crypt abscesses and submucosal erythrophagocytosis.

CONDITION:  Hemomelasma ilei

GENERAL DISCUSSION:

PATHOGENESIS:

TYPICAL CLINICAL FINDINGS:

TYPICAL GROSS FINDINGS:

TYPICAL LIGHT MICROSCOPIC FINDINGS:

DIFFERENTIAL DIAGNOSIS:

COMPARATIVE PATHOLOGY:

REFERENCES: 

  1. Gelberg, HB. Alimentary system and the peritoneum, omentum, mesentery, and peritoneal cavity. In: McGavin MD, Zachary JF, eds. Pathologic Basis of Veterinary Disease. 6th ed. St. Louis, MO: Elsevier; 2017:373.
  2. Buergelt CD, Del Piero F. Equine Pathology. Ames, IA: John Wiley & Sons, Inc.; 2014:159-160.
  3. Uzal FA, Plattner BL, Hostetter JM. In: Maxie MG, ed. Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals. Vol 2. 6th ed. Philadelphia, PA: Elsevier; 2016:216-217.


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