JPC SYSTEMIC PATHOLOGY
DIGESTIVE SYSTEM
December 2018
D-V26

Signalment (JPC #1380446):  Fingerling trout

HISTORY:  None

 

HISTOPATHOLOGIC DESCRIPTION:  Sagittal section, fingerling trout:  There is diffuse pancreatic lytic necrosis, characterized by loss of normal architecture and replacement with eosinophilic cellular and karyorrhectic debris, and infiltration by lymphocytes, plasma cells, and granulocytes.  Within the pyloric ceca there is extensive disruption, sloughing, and necrosis of the mucosa including multifocal single cell necrosis of the epithelium (McKnight cells).  The cecal lumen contains abundant cellular debris and basophilic flocculent material (mucus).

MORPHOLOGIC DIAGNOSIS:

  1. Pancreas: Necrosis and acinar loss, acute, diffuse, severe, trout (Salmon sp.), piscine.
  2. Pyloric ceca, mucosa: Necrosis, acute, diffuse, moderate, with McKnight cells.

ETIOLOGIC DIAGNOSIS:  Birnaviral pancreatic necrosis

CAUSE:  Infectious pancreatic necrosis virus (aquabirnavirus)

CONDITION:  Infectious pancreatic necrosis (IPN)

GENERAL DISCUSSION:

PATHOGENESIS:

TYPICAL CLINICAL FINDINGS:

TYPICAL GROSS FINDINGS:

TYPICAL LIGHT MICROSCOPIC FINDINGS:

ULTRASTRUCTURAL FINDINGS:  

ADDITIONAL DIAGNOSTIC TESTS:

DIFFERENTIAL DIAGNOSIS:

COMPARATIVE PATHOLOGY:

Other aquabirnaviruses:

Other birnaviruses:

REFERENCES:

  1. Noga EJ. Fish Disease: Diagnosis and Treatment. 2nd ed. Ames, IA: Wiley-Blackwell; 2010: 271-282, 300..


Click the slide to view.



Click on image for diagnostic series.



Back | Home | Contact Us | Links | Help |