JPC SYSTEMIC PATHOLOGY

INTEGUMENT SYSTEM

October 2016

I-N28 (NP)

 

Signalment (JPC #2233443): Age and breed unspecified dog

HISTORY:  A slow growing neoplasm removed from the 2nd digit of the left forepaw

HISTOPATHOLOGIC DESCRIPTION:  Haired skin, 2nd digit, left paw (per contributor):  Expanding the dermis and elevating the mildly hyperplastic epidermis, is a well vascularized, pedunculated, 2.5 x 1 cm mass which contains few dysplastic and haphazardly arranged hair follicles and adnexa.  The mass is composed of both loosely arranged and thick, tightly packed collagen bundles admixed with moderate numbers of reactive fibroblasts.  Near the tip of the mass, collagen bundles are separated by clear space and lymphatics are ectatic (edema).  Within the neck of the mass, perivascular connective tissue contains few scattered lymphocytes, plasma cells, macrophages and neutrophils.  There is diffuse, mild, hyperkeratosis, acanthosis, spongiosis and short, rarely anastamosing rete ridges.  Multifocally within the subjacent dermis, hair follicles and adnexa are surrounded by occasional lymphocytes, plasma cells, and macrophages. 

MORPHOLOGIC DIAGNOSIS:  Haired skin, 2nd digit, left forepaw (per contributor):  Acrochordon, breed not specified, canine.

CONDITION:  Acrochordon

SYNONYMS:  Fibroepithelial polyp, fibrovascular papilloma, skin tag, skin polyp

GENERAL DISCUSSION:

PATHOGENESIS:

TYPICAL CLINICAL FINDINGS:

TYPICAL GROSS FINDINGS:

TYPICAL LIGHT MICROSCOPIC FINDINGS:

DIFFERENTIAL DIAGNOSIS: 

COMPARATIVE:

REFERENCES:

  1. Brown PJ, Evans HK, et al. Fibroepithelial polyps of the vaginia in bitches: A historical and immunohistochemical study. J Comp Pathol. 2012; 147:181-185.
  2. Goldschmidt MH, Dunstan RW, Stannard AA, von Tscharner C, Walder EJ, Yager J. Histological Classification of Epithelial and Melanocytic Tumors of the Skin of Domestic Animals. Vol III. 2nd Series. Washington, DC:Armed Forces Institute of Pathology; 1998:36-37, 72.
  3. Gross TL, Ihrke PJ, Walder EJ, Affolter VK. Fibrous tumors. In: Skin Diseases of the Dog and Cat. Ames, IA:Blackwell Publishing; 2005:713-716.
  4. Scott DW, Miller WH, Griffin CE. Muller & Kirk"s Small Animal Dermatology. 6th ed. Philadelphia, PA:WB Saunders Co; 2001:1284.
  5. Sipos W, Griessler F, Schilcher F, Stumpf I, Pirker E, Schmoll F. Fibroepithelial hamartoma in a domestic pig. Vet Pathol. 2007; 44(3):411-413.


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